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MegaSporeBiotic™ boasts a 5-year shelf-life, does not require refrigeration, and maintains a healthy gut microbiome.","brand":"Microbiome Labs","offers":[{"title":"Default","offer_id":52278734520659,"sku":"TMC-52876","price":57.13,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1001\/4156\/4243\/files\/https_3A_2F_2Fprodwelldium.blob.core.windows.net_2Fproduction_2Fproduct-images_2F5a6d2a7e-82bb-4542-4f7d-08da78a4a19b_2FMBL-MegaSporeBiotic-PLUS-Bottle-Active-Bacteria-FRONT_2e9eeb3b-f719-4281-9c48-8b0d0f6ee926.webp?v=1783540357"},{"product_id":"mega-spore-biotic-uk-60-capsules","title":"Mega Spore Biotic, UK - 60 Capsules","description":"MegaSporeBiotic is a probiotic blend of 4 Bacillus spores that have been clinically shown to maintain healthy gut barrier function and overall immunity. The bi-phasic life cycle of the Bacillus spores allows them to remain dormant in harsh environments until they reach more favuorable environments like the human gastrointestinal tract. Once inside the large intestine, these dormant spores can change into their active, vegetative forms and begin colonizing in the gut. This unique probiotic blend aims to RECONDITION the gut instead of reseeding with probiotic strains that cannot survive digestion or colonize the gut. 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One of the most commonly known active ingredients in licorice is a saponin called glycyrrhizin that has been used as an emulsifier and sweetener in the food industry. However, most supplements contain deglycyrrhizinated licorice (DGL) because large amounts of glycyrrhizin have been associated with serious adverse side effects like elevated blood pressure and lowered potassium levels. Gutgard® licorice flavonoids are entirely different from DGL with respect to chemistry, composition, manufacturing, and mechanisms of action. While a classical extract of DGL does not contain any significant quantity of flavonoids, Gutgard® is standardized to contain more than 10% total flavonoids and less than 0.5% glycyrrhizin to avoid undesirable effects. More than 50 flavonoids have been identified in Gutgard® which have been shown to have beneficial activity for digestive complaints. In fact, Gutgard® licorice flavonoids have been shown to protect the stomach lining and balance Helicobacter pylori levels much more effectively than regular DGL extracts. Gutgard® licorice can also relieve occasional indigestion, bloating, and stomach pain at 150 mg\/day.  \u003cbr\u003e\u003cbr\u003eARTICHOKE LEAF EXTRACT | 320 mg  \u003cbr\u003eArtichoke (Cynara scolymus) leaf extract (ALE) has also been used in traditional medicine as a digestive aid. The bitter compounds, particularly cynaropicrin, are responsible for the digestive benefits of artichoke. ALE has been shown to increase bile production, protect the liver, balance blood lipids, and act as an antispasmodic. In 2003, German researchers demonstrated that 640 mg\/day of artichoke leaf extract significantly improved digestive symptoms like bloating and fullness as well as quality of life in 244 patients with functional dyspepsia. Though the study was conducted over 6 weeks, the majority of the treatment group saw relief of their digestive symptoms in the first week.  \u003cbr\u003e\u003cbr\u003eGINGER ROOT EXTRACT (20%) | 30 mg  \u003cbr\u003eGinger (Zingiber officinalis) has been used as a digestive aid in Eastern medicine for generations. Studies have demonstrated that ginger accelerates gastric emptying and can relieve occasional bouts of nausea and vomiting. Gingerols and shogaols, the active polyphenolic compounds in ginger, appear to be responsible for such effects by weakly inhibiting cholinergic M3 and serotonergic 5-HT3 receptors, whose temporary dysfunction is responsible for nausea, vomiting, and hypomotility. Ginger extracts with a higher gingerol content (20-30% gingerols) are stronger and more effective at relieving digestive discomforts. In 2015, an Italian study of 126 patients found that the daily combination of 40 mg of ginger extracts (25-30% gingerols) with 200 mg of artichoke leaf extracts reduced the severity and frequency of common digestive symptoms like nausea, bloating, early satiety, and abdominal pain 17% more effectively than just artichoke leaf extract alone. 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Not many people think of mucus as being protective, but it is the main interface between the human body and the outside world. The mucosal system contains 150 times more surface area than the skin, which makes it one of the most important immune barriers. 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However, most prebiotics on the market can feed both harmful and beneﬁcial gut bacteria, which can exacerbate digestive issues. Keystone bacteria like bacterium prausnitzii, and Biﬁdobacteria are very important for human health, but their populations can be easily diminished by antibiotics, stress, diet, glyphosate, and other environmental toxins.prausnitzii, and Bifidobacteria. 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